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相互作用

Cabotegravir + Magnesium citrate

重症度: 中等度

Cabotegravir and Magnesium citrate: moderate interaction.

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概要

Oral cabotegravir can chelate with polyvalent cations such as magnesium, lowering its absorption. This may reduce efficacy of the integrase inhibitor.

この相互作用をわかりやすく説明すると

Cabotegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cabotegravir belongs to Anti Virals; Magnesium citrate belongs to Gastrointestinal Tract.

エビデンスレベル: High

なぜ起こるのか

Chelation of cabotegravir by magnesium in the gut reduces absorption.

対処法

Take oral cabotegravir at least 2 hours before or 4 hours after magnesium citrate.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CabotegravirとMagnesium citrateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Cabotegravir with Magnesium citrate?

MediHelp rates the interaction as moderate. Cabotegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral cabotegravir can chelate with polyvalent cations such as magnesium, lowering its absorption. This may reduce efficacy of the integrase inhibitor.

How serious is the interaction between Cabotegravir and Magnesium citrate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral cabotegravir at least 2 hours before or 4 hours after magnesium citrate.

What other medicines interact with Magnesium citrate?

MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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