相互作用
Ciprofloxacin + Magnesium citrate
重症度: 重大
Ciprofloxacin and Magnesium citrate: major interaction.
最終更新日
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概要
Magnesium chelates ciprofloxacin in the gut and markedly reduces its absorption. This can cause subtherapeutic antibiotic levels and treatment failure.
この相互作用をわかりやすく説明すると
Ciprofloxacin and Magnesium citrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Magnesium citrate belongs to Gastrointestinal Tract.
なぜ起こるのか
Chelation of ciprofloxacin by polyvalent magnesium cations in the gastrointestinal tract reduces absorption.
対処法
Give oral ciprofloxacin at least 2 hours before or 6 hours after magnesium citrate. Avoid the combination if separation is impractical.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、CiprofloxacinとMagnesium citrateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium citrateのその他の相互作用
Ciprofloxacinのその他の相互作用
よくある質問
Can I take Ciprofloxacin with Magnesium citrate?
MediHelp rates the interaction as major. Ciprofloxacin and Magnesium citrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium chelates ciprofloxacin in the gut and markedly reduces its absorption. This can cause subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Magnesium citrate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after magnesium citrate. Avoid the combination if separation is impractical.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Baloxavir marboxil, Bictegravir, Cabotegravir. The full list is on the Magnesium citrate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
