相互作用
Bivalirudin + Eptifibatide
重症度: 重大
Bivalirudin and Eptifibatide: major interaction.
最終更新日
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概要
Bivalirudin may be combined with GP IIb/IIIa inhibitors in PCI, but bleeding risk rises. Events can be serious.
この相互作用をわかりやすく説明すると
Bivalirudin and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive effects of direct thrombin inhibition and platelet GP IIb/IIIa blockade.
対処法
Use only when protocol-directed; monitor ACT, hemoglobin, platelet count and access-site bleeding.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BivalirudinとEptifibatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eptifibatideのその他の相互作用
よくある質問
Can I take Bivalirudin with Eptifibatide?
MediHelp rates the interaction as major. Bivalirudin and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Bivalirudin may be combined with GP IIb/IIIa inhibitors in PCI, but bleeding risk rises. Events can be serious.
How serious is the interaction between Bivalirudin and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when protocol-directed; monitor ACT, hemoglobin, platelet count and access-site bleeding.
What other medicines interact with Eptifibatide?
MediHelp also lists interactions of Eptifibatide with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Eptifibatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。