相互作用
Bromocriptine + Dihydroergotamine intranasal
重症度: 重大
Bromocriptine and Dihydroergotamine intranasal: major interaction.
最終更新日
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概要
Intranasal dihydroergotamine is absorbed systemically and combined with bromocriptine may add to ergot-related vasoconstriction, causing hypertension, vasospasm or peripheral ischemia. The combination offers little benefit relative to its risk.
この相互作用をわかりやすく説明すると
Bromocriptine and Dihydroergotamine intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive pharmacodynamic vasoconstrictive and ergot-related effects at vascular receptors.
対処法
Avoid the combination and use a non-ergot migraine therapy if bromocriptine is required. If both are used, monitor blood pressure and for signs of ischemia.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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アカウントを作成してPro+トライアルを始めると、BromocriptineとDihydroergotamine intranasalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bromocriptineのその他の相互作用
よくある質問
Can I take Bromocriptine with Dihydroergotamine intranasal?
MediHelp rates the interaction as major. Bromocriptine and Dihydroergotamine intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Intranasal dihydroergotamine is absorbed systemically and combined with bromocriptine may add to ergot-related vasoconstriction, causing hypertension, vasospasm or peripheral ischemia. The combination offers little benefit relative to its risk.
How serious is the interaction between Bromocriptine and Dihydroergotamine intranasal?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-ergot migraine therapy if bromocriptine is required. If both are used, monitor blood pressure and for signs of ischemia.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
