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相互作用

Budesonide + Somatropin

重症度: 中等度

Budesonide and Somatropin: moderate interaction.

最終更新日

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概要

Glucocorticoids can inhibit the growth-promoting effects of somatropin, which matters in children treated for growth failure. Somatropin may also alter glucose tolerance, and corticosteroids add to this.

この相互作用をわかりやすく説明すると

Budesonide and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Budesonide belongs to Respiratory; Somatropin belongs to Endocrine.

エビデンスレベル: Moderate

なぜ起こるのか

Pharmacodynamic antagonism: glucocorticoids suppress growth and reduce IGF-1-mediated effects.

対処法

Use the lowest effective budesonide dose and monitor growth velocity and glucose. Adjust the somatropin dose if growth is inadequate.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、BudesonideとSomatropinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Budesonide with Somatropin?

MediHelp rates the interaction as moderate. Budesonide and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucocorticoids can inhibit the growth-promoting effects of somatropin, which matters in children treated for growth failure. Somatropin may also alter glucose tolerance, and corticosteroids add to this.

How serious is the interaction between Budesonide and Somatropin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective budesonide dose and monitor growth velocity and glucose. Adjust the somatropin dose if growth is inadequate.

What other medicines interact with Budesonide?

MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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