相互作用
Butabarbital + Melatonin
重症度: 中等度
Butabarbital and Melatonin: moderate interaction.
最終更新日
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概要
Butabarbital is a barbiturate sedative-hypnotic, and melatonin adds a mild sedative effect. Together they may increase drowsiness and next-day impairment.
この相互作用をわかりやすく説明すると
Butabarbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive CNS depression via GABA-A potentiation by the barbiturate and melatonin receptor-mediated sedation.
対処法
Avoid combining for sleep where possible; if used together, monitor for excessive sedation and advise against driving or operating machinery.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ButabarbitalとMelatoninの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Melatoninのその他の相互作用
よくある質問
Can I take Butabarbital with Melatonin?
MediHelp rates the interaction as moderate. Butabarbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butabarbital is a barbiturate sedative-hypnotic, and melatonin adds a mild sedative effect. Together they may increase drowsiness and next-day impairment.
How serious is the interaction between Butabarbital and Melatonin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining for sleep where possible; if used together, monitor for excessive sedation and advise against driving or operating machinery.
What other medicines interact with Melatonin?
MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
