相互作用
Butalbital + Melatonin
重症度: 中等度
Butalbital and Melatonin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Butalbital is a barbiturate that causes sedation, and melatonin may add to drowsiness. Impaired alertness and psychomotor performance are possible.
この相互作用をわかりやすく説明すると
Butalbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive CNS depression from barbiturate GABA-A potentiation and melatonin-mediated sedation.
対処法
Counsel patients about additive drowsiness and avoid driving until response is known; reduce or stop melatonin if excessive sedation occurs.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ButalbitalとMelatoninの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Melatoninのその他の相互作用
よくある質問
Can I take Butalbital with Melatonin?
MediHelp rates the interaction as moderate. Butalbital and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butalbital is a barbiturate that causes sedation, and melatonin may add to drowsiness. Impaired alertness and psychomotor performance are possible.
How serious is the interaction between Butalbital and Melatonin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about additive drowsiness and avoid driving until response is known; reduce or stop melatonin if excessive sedation occurs.
What other medicines interact with Melatonin?
MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
