相互作用
Calcium citrate + Etidronate
重症度: 中等度
Calcium citrate and Etidronate: moderate interaction.
最終更新日
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概要
Calcium citrate supplements taken with oral etidronate can chelate the drug and cut its absorption. Reduced exposure may lessen the effect on bone.
この相互作用をわかりやすく説明すると
Calcium citrate and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Divalent calcium cations chelate etidronate in the gastrointestinal tract, forming poorly absorbable complexes.
対処法
Separate calcium citrate from etidronate by at least 2 hours, taking etidronate fasting. In cyclic regimens, schedule calcium for the etidronate-free interval.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Calcium citrateとEtidronateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Etidronateのその他の相互作用
よくある質問
Can I take Calcium citrate with Etidronate?
MediHelp rates the interaction as moderate. Calcium citrate and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium citrate supplements taken with oral etidronate can chelate the drug and cut its absorption. Reduced exposure may lessen the effect on bone.
How serious is the interaction between Calcium citrate and Etidronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate calcium citrate from etidronate by at least 2 hours, taking etidronate fasting. In cyclic regimens, schedule calcium for the etidronate-free interval.
What other medicines interact with Etidronate?
MediHelp also lists interactions of Etidronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Etidronate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
