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相互作用

Calcium + Etidronate

重症度: 中等度

Calcium and Etidronate: moderate interaction.

最終更新日

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このページの臨床コンテンツは英語でのみ提供されています。

概要

Oral calcium forms poorly absorbed complexes with etidronate in the gut, reducing the amount of bisphosphonate absorbed. This can lessen its effect on bone.

この相互作用をわかりやすく説明すると

Calcium and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium belongs to Gastrointestinal Tract; Etidronate belongs to Musculoskeletal.

エビデンスレベル: High

なぜ起こるのか

Divalent calcium chelates the bisphosphonate in the gastrointestinal tract, inhibiting its absorption.

対処法

Take etidronate on an empty stomach and separate it from calcium-containing products by at least 2 hours, as directed by the product labeling.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CalciumとEtidronateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Calcium with Etidronate?

MediHelp rates the interaction as moderate. Calcium and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium forms poorly absorbed complexes with etidronate in the gut, reducing the amount of bisphosphonate absorbed. This can lessen its effect on bone.

How serious is the interaction between Calcium and Etidronate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take etidronate on an empty stomach and separate it from calcium-containing products by at least 2 hours, as directed by the product labeling.

What other medicines interact with Calcium?

MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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