相互作用
Carbamazepine + Maribavir
重症度: 中等度
Carbamazepine and Maribavir: moderate interaction.
最終更新日
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概要
Carbamazepine lowers maribavir concentrations and may compromise control of CMV infection.
この相互作用をわかりやすく説明すると
Carbamazepine and Maribavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Maribavir belongs to Anti Virals.
なぜ起こるのか
Carbamazepine induces CYP3A4, increasing maribavir metabolism.
対処法
If coadministration is needed, increase the maribavir dose as directed by labeling and monitor CMV viral load. Consider a non-inducing anticonvulsant where possible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CarbamazepineとMaribavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Maribavirのその他の相互作用
Carbamazepineのその他の相互作用
よくある質問
Can I take Carbamazepine with Maribavir?
MediHelp rates the interaction as moderate. Carbamazepine and Maribavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine lowers maribavir concentrations and may compromise control of CMV infection.
How serious is the interaction between Carbamazepine and Maribavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If coadministration is needed, increase the maribavir dose as directed by labeling and monitor CMV viral load. Consider a non-inducing anticonvulsant where possible.
What other medicines interact with Maribavir?
MediHelp also lists interactions of Maribavir with, for example, Ganciclovir, Rifampicin, Valganciclovir. The full list is on the Maribavir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
