相互作用
Digoxin + Maribavir
重症度: 中等度
Digoxin and Maribavir: moderate interaction.
最終更新日
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概要
Maribavir raises digoxin concentrations. Because digoxin has a narrow therapeutic index, this can lead to toxicity such as arrhythmias, nausea and visual disturbances.
この相互作用をわかりやすく説明すると
Digoxin and Maribavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Maribavir belongs to Anti Virals.
なぜ起こるのか
Maribavir inhibits intestinal P-glycoprotein, increasing digoxin absorption.
対処法
Monitor serum digoxin concentrations and clinical signs of toxicity when starting or stopping maribavir. Reduce the digoxin dose if needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DigoxinとMaribavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Maribavirのその他の相互作用
Digoxinのその他の相互作用
よくある質問
Can I take Digoxin with Maribavir?
MediHelp rates the interaction as moderate. Digoxin and Maribavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maribavir raises digoxin concentrations. Because digoxin has a narrow therapeutic index, this can lead to toxicity such as arrhythmias, nausea and visual disturbances.
How serious is the interaction between Digoxin and Maribavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum digoxin concentrations and clinical signs of toxicity when starting or stopping maribavir. Reduce the digoxin dose if needed.
What other medicines interact with Maribavir?
MediHelp also lists interactions of Maribavir with, for example, Ganciclovir, Rifampicin, Valganciclovir. The full list is on the Maribavir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
