相互作用
Cefepime + Microbiota
重症度: 中等度
Cefepime and Microbiota: moderate interaction.
最終更新日
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概要
Oral microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is partly excreted into the gut lumen may reduce the viability of the spores and blunt the preventive effect against recurrent Clostridioides difficile infection.
この相互作用をわかりやすく説明すると
Cefepime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
The antibacterial activity of the cephalosporin can reduce the viability of the live bacterial spores in the product.
対処法
Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefepimeとMicrobiotaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefepimeのその他の相互作用
よくある質問
Can I take Cefepime with Microbiota?
MediHelp rates the interaction as moderate. Cefepime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is partly excreted into the gut lumen may reduce the viability of the spores and blunt the preventive effect against recurrent Clostridioides difficile infection.
How serious is the interaction between Cefepime and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course before starting oral microbiota therapy, and keep the labeled interval after the last antibiotic dose (typically 2 to 4 days).
What other medicines interact with Cefepime?
MediHelp also lists interactions of Cefepime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Cefepime page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
