相互作用
Cefixime + Typhoid vaccine live
重症度: 重大
Cefixime and Typhoid vaccine live: major interaction.
最終更新日
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概要
Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi replicating in the gut. Cefixime is used to treat typhoid and may reduce vaccine viability and the immune response.
この相互作用をわかりやすく説明すると
Cefixime and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Antibacterial activity inhibits the live attenuated Salmonella strain, reducing immunogenicity.
対処法
Give live oral typhoid vaccine at least 3 days after the last cefixime dose, or vaccinate beforehand. Use the inactivated parenteral vaccine if timing cannot be separated.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefiximeとTyphoid vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cefiximeのその他の相互作用
よくある質問
Can I take Cefixime with Typhoid vaccine live?
MediHelp rates the interaction as major. Cefixime and Typhoid vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral live typhoid vaccine depends on viable attenuated Salmonella Typhi replicating in the gut. Cefixime is used to treat typhoid and may reduce vaccine viability and the immune response.
How serious is the interaction between Cefixime and Typhoid vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give live oral typhoid vaccine at least 3 days after the last cefixime dose, or vaccinate beforehand. Use the inactivated parenteral vaccine if timing cannot be separated.
What other medicines interact with Cefixime?
MediHelp also lists interactions of Cefixime with, for example, Cholera vaccine, Kanamycin, Microbiota. The full list is on the Cefixime page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
