相互作用
Chloroquine + Quinidine
重症度: 併用禁忌
Chloroquine and Quinidine: contraindicated interaction.
最終更新日
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概要
Quinidine can raise chloroquine levels and both drugs lengthen the QT interval. Torsades de pointes is a concern with this pairing.
この相互作用をわかりやすく説明すると
Chloroquine and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Chloroquine belongs to Anti Parasitic; Quinidine belongs to Anti Parasitic.
なぜ起こるのか
Additive QTc prolongation; quinidine may reduce chloroquine clearance
対処法
Avoid; use an alternative antimalarial or antiarrhythmic.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ChloroquineとQuinidineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Chloroquineのその他の相互作用
Quinidineのその他の相互作用
よくある質問
Can I take Chloroquine with Quinidine?
MediHelp rates the interaction as contraindicated. Chloroquine and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Quinidine can raise chloroquine levels and both drugs lengthen the QT interval. Torsades de pointes is a concern with this pairing.
How serious is the interaction between Chloroquine and Quinidine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; use an alternative antimalarial or antiarrhythmic.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
