相互作用
Chloroquine + Dronedarone
重症度: 併用禁忌
Chloroquine and Dronedarone: contraindicated interaction.
最終更新日
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概要
Both drugs prolong the QT interval, and dronedarone labeling advises against combination with QT-prolonging agents. The combination increases the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Chloroquine and Dronedarone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Chloroquine belongs to Anti Parasitic; Dronedarone belongs to Cardiovascular.
なぜ起こるのか
Additive QT prolongation through cardiac ion channel blockade.
対処法
Do not combine; select an alternative antimalarial or antiarrhythmic.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ChloroquineとDronedaroneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Chloroquineのその他の相互作用
Dronedaroneのその他の相互作用
よくある質問
Can I take Chloroquine with Dronedarone?
MediHelp rates the interaction as contraindicated. Chloroquine and Dronedarone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, and dronedarone labeling advises against combination with QT-prolonging agents. The combination increases the risk of torsades de pointes.
How serious is the interaction between Chloroquine and Dronedarone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; select an alternative antimalarial or antiarrhythmic.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Droperidol. The full list is on the Chloroquine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
