相互作用
Chlorpromazine + Droperidol
重症度: 併用禁忌
Chlorpromazine and Droperidol: contraindicated interaction.
最終更新日
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概要
Both drugs are dopamine antagonists that prolong the QT interval, and droperidol carries a boxed warning for torsades de pointes. Combined use markedly increases arrhythmia risk and additive sedation.
この相互作用をわかりやすく説明すると
Chlorpromazine and Droperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive blockade of cardiac potassium channels with QT prolongation, plus additive CNS depression.
対処法
Avoid using together; select an antiemetic or sedative without QT effects. If unavoidable, use continuous ECG monitoring and correct electrolytes.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ChlorpromazineとDroperidolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Chlorpromazineのその他の相互作用
よくある質問
Can I take Chlorpromazine with Droperidol?
MediHelp rates the interaction as contraindicated. Chlorpromazine and Droperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs are dopamine antagonists that prolong the QT interval, and droperidol carries a boxed warning for torsades de pointes. Combined use markedly increases arrhythmia risk and additive sedation.
How serious is the interaction between Chlorpromazine and Droperidol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using together; select an antiemetic or sedative without QT effects. If unavoidable, use continuous ECG monitoring and correct electrolytes.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Chlorpromazine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
