相互作用
Cidofovir + Tobramycin
重症度: 併用禁忌
Cidofovir and Tobramycin: contraindicated interaction.
最終更新日
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概要
Both agents are toxic to the renal tubule, so together they can cause serious acute kidney injury. Cidofovir labeling contraindicates its use with other nephrotoxic drugs such as aminoglycosides.
この相互作用をわかりやすく説明すると
Cidofovir and Tobramycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cidofovir belongs to Anti Virals; Tobramycin belongs to Anti Bacterial.
なぜ起こるのか
Additive direct tubular nephrotoxicity.
対処法
Do not co-administer; stop tobramycin at least 7 days before cidofovir or select a non-nephrotoxic alternative.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CidofovirとTobramycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Tobramycinのその他の相互作用
Cidofovirのその他の相互作用
よくある質問
Can I take Cidofovir with Tobramycin?
MediHelp rates the interaction as contraindicated. Cidofovir and Tobramycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are toxic to the renal tubule, so together they can cause serious acute kidney injury. Cidofovir labeling contraindicates its use with other nephrotoxic drugs such as aminoglycosides.
How serious is the interaction between Cidofovir and Tobramycin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; stop tobramycin at least 7 days before cidofovir or select a non-nephrotoxic alternative.
What other medicines interact with Tobramycin?
MediHelp also lists interactions of Tobramycin with, for example, Adefovir, Amikacin, Amphotericin b deoxycholate. The full list is on the Tobramycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
