相互作用
Ciprofloxacin + Sevelamer
重症度: 中等度
Ciprofloxacin and Sevelamer: moderate interaction.
最終更新日
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概要
Sevelamer binds oral ciprofloxacin in the gut and markedly lowers its absorption. This can result in subtherapeutic antibiotic levels and treatment failure.
この相互作用をわかりやすく説明すると
Ciprofloxacin and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Sevelamer belongs to Miscellaneous.
なぜ起こるのか
Binding of ciprofloxacin to sevelamer in the gastrointestinal tract reduces its absorption.
対処法
Give oral ciprofloxacin at least 2 hours before or 6 hours after sevelamer. Monitor for clinical response to the infection.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CiprofloxacinとSevelamerの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ciprofloxacinのその他の相互作用
Sevelamerのその他の相互作用
よくある質問
Can I take Ciprofloxacin with Sevelamer?
MediHelp rates the interaction as moderate. Ciprofloxacin and Sevelamer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sevelamer binds oral ciprofloxacin in the gut and markedly lowers its absorption. This can result in subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Sevelamer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after sevelamer. Monitor for clinical response to the infection.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
