相互作用
Copper + Penicillamine
重症度: 中等度
Copper and Penicillamine: moderate interaction.
最終更新日
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概要
Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
この相互作用をわかりやすく説明すると
Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
なぜ起こるのか
Pharmacodynamic antagonism, since penicillamine chelates copper and promotes its urinary excretion.
対処法
Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CopperとPenicillamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Penicillamineのその他の相互作用
Copperのその他の相互作用
よくある質問
Can I take Copper with Penicillamine?
MediHelp rates the interaction as moderate. Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
How serious is the interaction between Copper and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
