相互作用
Copper + Trientine
重症度: 中等度
Copper and Trientine: moderate interaction.
最終更新日
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概要
Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.
この相互作用をわかりやすく説明すると
Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Trientine belongs to Miscellaneous.
なぜ起こるのか
Trientine chelates copper, increasing urinary excretion and limiting absorption.
対処法
Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CopperとTrientineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Copperのその他の相互作用
Trientineのその他の相互作用
よくある質問
Can I take Copper with Trientine?
MediHelp rates the interaction as moderate. Copper and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Trientine chelates copper and promotes its elimination, which is the intended therapeutic effect in Wilson's disease. Copper supplementation would oppose this, and excessive treatment can cause copper deficiency.
How serious is the interaction between Copper and Trientine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with trientine for Wilson's disease. Monitor serum and urinary copper and watch for over-treatment such as anemia.
What other medicines interact with Copper?
MediHelp also lists interactions of Copper with, for example, Omadacycline, Penicillamine, Sarecycline. The full list is on the Copper page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
