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相互作用

Ferrous sulfate + Trientine

重症度: 中等度

Ferrous sulfate and Trientine: moderate interaction.

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概要

Iron and trientine chelate each other in the gut, reducing absorption of both. Trientine efficacy in copper removal may drop, and the iron may be less effective as well.

この相互作用をわかりやすく説明すると

Ferrous sulfate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ferrous sulfate belongs to Miscellaneous; Trientine belongs to Miscellaneous.

エビデンスレベル: Moderate

なぜ起こるのか

Mutual chelation in the gastrointestinal tract forms poorly absorbed complexes.

対処法

Separate iron and trientine by at least 2 hours. Monitor copper indices in Wilson disease and iron indices.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Ferrous sulfateとTrientineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Ferrous sulfate with Trientine?

MediHelp rates the interaction as moderate. Ferrous sulfate and Trientine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron and trientine chelate each other in the gut, reducing absorption of both. Trientine efficacy in copper removal may drop, and the iron may be less effective as well.

How serious is the interaction between Ferrous sulfate and Trientine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate iron and trientine by at least 2 hours. Monitor copper indices in Wilson disease and iron indices.

What other medicines interact with Ferrous sulfate?

MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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