相互作用
Cyclosporine + Echinacea
重症度: 中等度
Cyclosporine and Echinacea: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Echinacea's immunostimulatory activity may theoretically counteract cyclosporine immunosuppression in transplant or autoimmune patients, raising rejection or flare risk. Some data suggest echinacea may also modestly affect CYP3A activity, though the findings are inconsistent.
この相互作用をわかりやすく説明すると
Cyclosporine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Theoretical pharmacodynamic antagonism by immune stimulation, with possible minor CYP3A modulation.
対処法
Advise transplant recipients to avoid echinacea. If used, monitor cyclosporine trough concentrations and graft function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CyclosporineとEchinaceaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Echinaceaのその他の相互作用
よくある質問
Can I take Cyclosporine with Echinacea?
MediHelp rates the interaction as moderate. Cyclosporine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea's immunostimulatory activity may theoretically counteract cyclosporine immunosuppression in transplant or autoimmune patients, raising rejection or flare risk. Some data suggest echinacea may also modestly affect CYP3A activity, though the findings are inconsistent.
How serious is the interaction between Cyclosporine and Echinacea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant recipients to avoid echinacea. If used, monitor cyclosporine trough concentrations and graft function.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Antithymocyte globulin rabbit. The full list is on the Echinacea page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
