相互作用
Azathioprine + Echinacea
重症度: 中等度
Azathioprine and Echinacea: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Echinacea has immunostimulant properties that could theoretically oppose the immunosuppressive effect of azathioprine. This could reduce disease control or graft protection, although clinical data are lacking.
この相互作用をわかりやすく説明すると
Azathioprine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azathioprine belongs to Gastrointestinal Tract; Echinacea belongs to Gastrointestinal Tract.
なぜ起こるのか
Theoretical pharmacodynamic antagonism between immune stimulation by echinacea and immunosuppression by azathioprine; not well established.
対処法
Advise patients on azathioprine to avoid echinacea products. If used, monitor for loss of disease control or signs of graft rejection.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzathioprineとEchinaceaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Azathioprineのその他の相互作用
Echinaceaのその他の相互作用
よくある質問
Can I take Azathioprine with Echinacea?
MediHelp rates the interaction as moderate. Azathioprine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea has immunostimulant properties that could theoretically oppose the immunosuppressive effect of azathioprine. This could reduce disease control or graft protection, although clinical data are lacking.
How serious is the interaction between Azathioprine and Echinacea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients on azathioprine to avoid echinacea products. If used, monitor for loss of disease control or signs of graft rejection.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
