相互作用
Dabigatran etexilate + Mifepristone
重症度: 併用禁忌
Dabigatran etexilate and Mifepristone: contraindicated interaction.
最終更新日
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概要
Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dabigatran etexilate, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.
この相互作用をわかりやすく説明すると
Dabigatran etexilate and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dabigatran etexilate belongs to Cardiovascular; Mifepristone belongs to Endocrine.
なぜ起こるのか
Additive haemorrhagic risk (uterine bleeding plus anticoagulation)
対処法
Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Dabigatran etexilateとMifepristoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dabigatran etexilateのその他の相互作用
Mifepristoneのその他の相互作用
よくある質問
Can I take Dabigatran etexilate with Mifepristone?
MediHelp rates the interaction as contraindicated. Dabigatran etexilate and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dabigatran etexilate, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.
How serious is the interaction between Dabigatran etexilate and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Dabigatran etexilate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
