相互作用
Apixaban + Mifepristone
重症度: 併用禁忌
Apixaban and Mifepristone: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Mifepristone labelling excludes patients receiving anticoagulants because prolonged or heavy bleeding can follow. Apixaban therapy therefore increases the haemorrhagic risk of the mifepristone regimen.
この相互作用をわかりやすく説明すると
Apixaban and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Apixaban belongs to Cardiovascular; Mifepristone belongs to Endocrine.
なぜ起こるのか
Additive bleeding risk with anticoagulant therapy
対処法
Avoid; assess alternatives to pharmacological abortion or temporarily hold the anticoagulant under specialist advice.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ApixabanとMifepristoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Apixabanのその他の相互作用
Mifepristoneのその他の相互作用
よくある質問
Can I take Apixaban with Mifepristone?
MediHelp rates the interaction as contraindicated. Apixaban and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone labelling excludes patients receiving anticoagulants because prolonged or heavy bleeding can follow. Apixaban therapy therefore increases the haemorrhagic risk of the mifepristone regimen.
How serious is the interaction between Apixaban and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; assess alternatives to pharmacological abortion or temporarily hold the anticoagulant under specialist advice.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。