相互作用
Dapagliflozin-metformin + Liothyronine
重症度: 中等度
Dapagliflozin-metformin and Liothyronine: moderate interaction.
最終更新日
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概要
Thyroid hormones can raise blood glucose and increase antidiabetic requirements, particularly when doses are excessive. Glycemic control may worsen after starting liothyronine or increasing its dose.
この相互作用をわかりやすく説明すると
Dapagliflozin-metformin and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dapagliflozin-metformin belongs to Endocrine; Liothyronine belongs to Endocrine.
なぜ起こるのか
Thyroid hormone increases hepatic glucose production and metabolic rate, opposing glucose-lowering drugs.
対処法
Monitor glucose when starting or changing liothyronine and adjust antidiabetic doses if needed. Watch for hypoglycemia if thyroid dose is reduced.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Dapagliflozin-metforminとLiothyronineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dapagliflozin-metforminのその他の相互作用
Liothyronineのその他の相互作用
よくある質問
Can I take Dapagliflozin-metformin with Liothyronine?
MediHelp rates the interaction as moderate. Dapagliflozin-metformin and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thyroid hormones can raise blood glucose and increase antidiabetic requirements, particularly when doses are excessive. Glycemic control may worsen after starting liothyronine or increasing its dose.
How serious is the interaction between Dapagliflozin-metformin and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting or changing liothyronine and adjust antidiabetic doses if needed. Watch for hypoglycemia if thyroid dose is reduced.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
