相互作用
Dengue vaccine + Idarubicin
重症度: 重大
Dengue vaccine and Idarubicin: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Dengue vaccine is a live attenuated vaccine, and cytotoxic chemotherapy can blunt the immune response and raise the risk of vaccine-related infection. Immunity may be inadequate and the vaccine could cause disease in immunosuppressed patients.
この相互作用をわかりやすく説明すると
Dengue vaccine and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Chemotherapy-induced immunosuppression reduces vaccine response and permits replication of live vaccine virus.
対処法
Avoid giving the live dengue vaccine during chemotherapy and until immune recovery. Plan vaccination well before treatment or after recovery.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Dengue vaccineとIdarubicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Idarubicinのその他の相互作用
よくある質問
Can I take Dengue vaccine with Idarubicin?
MediHelp rates the interaction as major. Dengue vaccine and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine, and cytotoxic chemotherapy can blunt the immune response and raise the risk of vaccine-related infection. Immunity may be inadequate and the vaccine could cause disease in immunosuppressed patients.
How serious is the interaction between Dengue vaccine and Idarubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the live dengue vaccine during chemotherapy and until immune recovery. Plan vaccination well before treatment or after recovery.
What other medicines interact with Idarubicin?
MediHelp also lists interactions of Idarubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclophosphamide. The full list is on the Idarubicin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
