相互作用
Dexamethasone + Smallpox vaccine live
重症度: 併用禁忌
Dexamethasone and Smallpox vaccine live: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
この相互作用をわかりやすく説明すると
Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression permits uncontrolled replication of live vaccinia virus.
対処法
Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DexamethasoneとSmallpox vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasoneのその他の相互作用
よくある質問
Can I take Dexamethasone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
How serious is the interaction between Dexamethasone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
