相互作用
Dexamethasone + Varicella virus vaccine live
重症度: 併用禁忌
Dexamethasone and Varicella virus vaccine live: contraindicated interaction.
最終更新日
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概要
Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.
この相互作用をわかりやすく説明すると
Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid-induced suppression of cellular immunity permits uncontrolled replication of the attenuated virus.
対処法
Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DexamethasoneとVaricella virus vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasoneのその他の相互作用
よくある質問
Can I take Dexamethasone with Varicella virus vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.
How serious is the interaction between Dexamethasone and Varicella virus vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
