相互作用
Dexamethasone + Yellow fever vaccine
重症度: 併用禁忌
Dexamethasone and Yellow fever vaccine: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
この相互作用をわかりやすく説明すると
Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid-induced immunosuppression impairs control of attenuated virus replication and blunts the immune response.
対処法
Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DexamethasoneとYellow fever vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dexamethasoneのその他の相互作用
よくある質問
Can I take Dexamethasone with Yellow fever vaccine?
MediHelp rates the interaction as contraindicated. Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
How serious is the interaction between Dexamethasone and Yellow fever vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
