相互作用
Docusate + Mineral oil
重症度: 中等度
Docusate and Mineral oil: moderate interaction.
最終更新日
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概要
Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
この相互作用をわかりやすく説明すると
Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Docusate belongs to Gastrointestinal Tract; Mineral oil belongs to Gastrointestinal Tract.
なぜ起こるのか
Docusate's surfactant action emulsifies mineral oil and enhances its intestinal absorption.
対処法
Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DocusateとMineral oilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Mineral oilのその他の相互作用
よくある質問
Can I take Docusate with Mineral oil?
MediHelp rates the interaction as moderate. Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
How serious is the interaction between Docusate and Mineral oil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
What other medicines interact with Mineral oil?
MediHelp also lists interactions of Mineral oil with, for example, Vitamin k1, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
