相互作用
Mineral oil + Vitamin k1
重症度: 中等度
Mineral oil and Vitamin k1: moderate interaction.
最終更新日
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概要
Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.
この相互作用をわかりやすく説明すると
Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Mineral oil belongs to Gastrointestinal Tract; Vitamin k1 belongs to Cardiovascular.
なぜ起こるのか
Mineral oil dissolves vitamin K in the gut lumen and carries it out in the stool, reducing absorption.
対処法
Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Mineral oilとVitamin k1の臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Mineral oilのその他の相互作用
Vitamin k1のその他の相互作用
よくある質問
Can I take Mineral oil with Vitamin k1?
MediHelp rates the interaction as moderate. Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.
How serious is the interaction between Mineral oil and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.
What other medicines interact with Mineral oil?
MediHelp also lists interactions of Mineral oil with, for example, Docusate, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
