相互作用
Droperidol + Moxifloxacin
重症度: 併用禁忌
Droperidol and Moxifloxacin: contraindicated interaction.
最終更新日
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概要
Droperidol carries a boxed warning for QT prolongation and torsades de pointes, and moxifloxacin adds to that effect. Co-administration substantially raises the arrhythmia risk.
この相互作用をわかりやすく説明すると
Droperidol and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive pharmacodynamic QT prolongation.
対処法
Avoid the combination and use a non-QT-prolonging antiemetic or antibiotic. If unavoidable, obtain an ECG and monitor continuously.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DroperidolとMoxifloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Moxifloxacinのその他の相互作用
よくある質問
Can I take Droperidol with Moxifloxacin?
MediHelp rates the interaction as contraindicated. Droperidol and Moxifloxacin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Droperidol carries a boxed warning for QT prolongation and torsades de pointes, and moxifloxacin adds to that effect. Co-administration substantially raises the arrhythmia risk.
How serious is the interaction between Droperidol and Moxifloxacin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antiemetic or antibiotic. If unavoidable, obtain an ECG and monitor continuously.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
