相互作用
Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir
重症度: 併用禁忌
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir: contraindicated interaction.
最終更新日
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概要
The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.
この相互作用をわかりやすく説明すると
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Therapeutic duplication of two integrase strand transfer inhibitors; no established pharmacokinetic mechanism.
対処法
Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Elvitegravir / cobicistat / emtricitabine / tenofovir dfとRaltegravirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Raltegravirのその他の相互作用
よくある質問
Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Raltegravir?
MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.
How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.
What other medicines interact with Raltegravir?
MediHelp also lists interactions of Raltegravir with, for example, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate, Aluminum hydroxide. The full list is on the Raltegravir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
