相互作用
Ergoloid mesylates + Sumatriptan
重症度: 併用禁忌
Ergoloid mesylates and Sumatriptan: contraindicated interaction.
最終更新日
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概要
Both drugs can constrict blood vessels, so taking them close together may produce prolonged vasospasm and reduced blood flow to the heart, brain or limbs. Ergoloid mesylates has weaker vasoconstrictor activity than classic ergot alkaloids, but labeling for triptans still advises against combining them with ergot-type drugs.
この相互作用をわかりやすく説明すると
Ergoloid mesylates and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive vasoconstriction through 5-HT1B/1D agonism (triptan) and ergot-derived serotonergic and adrenergic receptor effects.
対処法
Avoid concurrent use and keep at least 24 hours between a triptan and an ergot-type drug. Choose a single agent for the acute indication.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、Ergoloid mesylatesとSumatriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Sumatriptanのその他の相互作用
よくある質問
Can I take Ergoloid mesylates with Sumatriptan?
MediHelp rates the interaction as contraindicated. Ergoloid mesylates and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs can constrict blood vessels, so taking them close together may produce prolonged vasospasm and reduced blood flow to the heart, brain or limbs. Ergoloid mesylates has weaker vasoconstrictor activity than classic ergot alkaloids, but labeling for triptans still advises against combining them with ergot-type drugs.
How serious is the interaction between Ergoloid mesylates and Sumatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and keep at least 24 hours between a triptan and an ergot-type drug. Choose a single agent for the acute indication.
What other medicines interact with Sumatriptan?
MediHelp also lists interactions of Sumatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Sumatriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
