相互作用
Ergotamine + Sumatriptan
重症度: 併用禁忌
Ergotamine and Sumatriptan: contraindicated interaction.
最終更新日
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概要
Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
この相互作用をわかりやすく説明すると
Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ergotamine belongs to Central Nervous System; Sumatriptan belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction through serotonin receptors
対処法
Do not administer within 24 hours of each other.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、ErgotamineとSumatriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Sumatriptanのその他の相互作用
Ergotamineのその他の相互作用
よくある質問
Can I take Ergotamine with Sumatriptan?
MediHelp rates the interaction as contraindicated. Ergotamine and Sumatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and sumatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
How serious is the interaction between Ergotamine and Sumatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.
What other medicines interact with Sumatriptan?
MediHelp also lists interactions of Sumatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Sumatriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
