相互作用
Ethanol + Oxymorphone
重症度: 併用禁忌
Ethanol and Oxymorphone: contraindicated interaction.
最終更新日
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概要
Alcohol taken with oxymorphone increases sedation and respiratory depression and can be fatal. With the extended-release oxymorphone formulation, alcohol can also cause rapid release of the whole dose (dose dumping), leading to a potentially lethal overdose.
この相互作用をわかりやすく説明すると
Ethanol and Oxymorphone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Additive CNS depression, plus alcohol-induced disruption of the extended-release formulation that raises peak oxymorphone exposure.
対処法
Instruct patients to avoid alcohol and any alcohol-containing medicines during oxymorphone therapy. Extended-release oxymorphone is contraindicated with alcohol.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EthanolとOxymorphoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Oxymorphoneのその他の相互作用
よくある質問
Can I take Ethanol with Oxymorphone?
MediHelp rates the interaction as contraindicated. Ethanol and Oxymorphone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Alcohol taken with oxymorphone increases sedation and respiratory depression and can be fatal. With the extended-release oxymorphone formulation, alcohol can also cause rapid release of the whole dose (dose dumping), leading to a potentially lethal overdose.
How serious is the interaction between Ethanol and Oxymorphone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Instruct patients to avoid alcohol and any alcohol-containing medicines during oxymorphone therapy. Extended-release oxymorphone is contraindicated with alcohol.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Oxymorphone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
