相互作用
Golimumab + Measles vaccine
重症度: 併用禁忌
Golimumab and Measles vaccine: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
この相互作用をわかりやすく説明すると
Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
TNF-alpha blockade impairs immune control of replicating live attenuated virus.
対処法
Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、GolimumabとMeasles vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Golimumabのその他の相互作用
よくある質問
Can I take Golimumab with Measles vaccine?
MediHelp rates the interaction as contraindicated. Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
How serious is the interaction between Golimumab and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
