相互作用
Indacaterol-glycopyrronium + Revefenacin
重症度: 重大
Indacaterol-glycopyrronium and Revefenacin: major interaction.
最終更新日
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概要
Revefenacin is an inhaled long-acting muscarinic antagonist, as is glycopyrronium, so the two duplicate anticholinergic therapy. Combined use may increase dry mouth, urinary retention, constipation, glaucoma risk and tachycardia.
この相互作用をわかりやすく説明すると
Indacaterol-glycopyrronium and Revefenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Indacaterol-glycopyrronium belongs to Respiratory; Revefenacin belongs to Respiratory.
なぜ起こるのか
Additive antimuscarinic effects from two long-acting muscarinic antagonists.
対処法
Avoid using two long-acting anticholinergics together and pick a single LAMA-containing regimen. Monitor for anticholinergic effects if the overlap occurs during a switch.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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アカウントを作成してPro+トライアルを始めると、Indacaterol-glycopyrroniumとRevefenacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Indacaterol-glycopyrroniumのその他の相互作用
Revefenacinのその他の相互作用
よくある質問
Can I take Indacaterol-glycopyrronium with Revefenacin?
MediHelp rates the interaction as major. Indacaterol-glycopyrronium and Revefenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Revefenacin is an inhaled long-acting muscarinic antagonist, as is glycopyrronium, so the two duplicate anticholinergic therapy. Combined use may increase dry mouth, urinary retention, constipation, glaucoma risk and tachycardia.
How serious is the interaction between Indacaterol-glycopyrronium and Revefenacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two long-acting anticholinergics together and pick a single LAMA-containing regimen. Monitor for anticholinergic effects if the overlap occurs during a switch.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
