相互作用
Amisulpride + Indacaterol-glycopyrronium
重症度: 重大
Amisulpride and Indacaterol-glycopyrronium: major interaction.
最終更新日
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概要
Amisulpride causes dose-related QT prolongation, and indacaterol can add to arrhythmia risk through hypokalemia and tachycardia.
この相互作用をわかりやすく説明すると
Amisulpride and Indacaterol-glycopyrronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Indacaterol-glycopyrronium belongs to Respiratory.
なぜ起こるのか
Additive QT prolongation with beta-2 agonist induced hypokalemia.
対処法
Obtain ECG and correct electrolytes; monitor QTc during coadministration or choose an alternative.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmisulprideとIndacaterol-glycopyrroniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Indacaterol-glycopyrroniumのその他の相互作用
Amisulprideのその他の相互作用
よくある質問
Can I take Amisulpride with Indacaterol-glycopyrronium?
MediHelp rates the interaction as major. Amisulpride and Indacaterol-glycopyrronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride causes dose-related QT prolongation, and indacaterol can add to arrhythmia risk through hypokalemia and tachycardia.
How serious is the interaction between Amisulpride and Indacaterol-glycopyrronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain ECG and correct electrolytes; monitor QTc during coadministration or choose an alternative.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Arformoterol, Arsenic trioxide, Betaxolol. The full list is on the Indacaterol-glycopyrronium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
