相互作用
Influenza virus vaccine quadrivalent intranasal + Mercaptopurine
重症度: 併用禁忌
Influenza virus vaccine quadrivalent intranasal and Mercaptopurine: contraindicated interaction.
最終更新日
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概要
The intranasal vaccine contains live attenuated virus, which may replicate more in immunosuppressed patients. Mercaptopurine also may reduce the immune response.
この相互作用をわかりやすく説明すると
Influenza virus vaccine quadrivalent intranasal and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Immunosuppression impairs control of live attenuated virus replication.
対処法
Avoid the live intranasal vaccine in patients on mercaptopurine and use an inactivated injectable influenza vaccine instead.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Influenza virus vaccine quadrivalent intranasalとMercaptopurineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Mercaptopurineのその他の相互作用
よくある質問
Can I take Influenza virus vaccine quadrivalent intranasal with Mercaptopurine?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Mercaptopurine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal vaccine contains live attenuated virus, which may replicate more in immunosuppressed patients. Mercaptopurine also may reduce the immune response.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Mercaptopurine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on mercaptopurine and use an inactivated injectable influenza vaccine instead.
What other medicines interact with Mercaptopurine?
MediHelp also lists interactions of Mercaptopurine with, for example, Adenovirus types 4 and 7 live, Azathioprine, Bcg vaccine live. The full list is on the Mercaptopurine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
