相互作用
Insulin glargine + Insulin glargine-lixisenatide
重症度: 重大
Insulin glargine and Insulin glargine-lixisenatide: major interaction.
最終更新日
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概要
The combination product already contains insulin glargine, so adding separate glargine duplicates the same basal insulin. This risks overdose and significant hypoglycemia.
この相互作用をわかりやすく説明すると
Insulin glargine and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glargine belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
なぜ起こるのか
Therapeutic duplication leading to additive insulin effect.
対処法
Avoid concurrent use; count glargine from the combination product toward the total basal dose. Use a single product and monitor glucose closely if transitioning.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Insulin glargineとInsulin glargine-lixisenatideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin glargine-lixisenatideのその他の相互作用
Insulin glargineのその他の相互作用
よくある質問
Can I take Insulin glargine with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Insulin glargine and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The combination product already contains insulin glargine, so adding separate glargine duplicates the same basal insulin. This risks overdose and significant hypoglycemia.
How serious is the interaction between Insulin glargine and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; count glargine from the combination product toward the total basal dose. Use a single product and monitor glucose closely if transitioning.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。