相互作用
Linezolid + Ozanimod
重症度: 併用禁忌
Linezolid and Ozanimod: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
この相互作用をわかりやすく説明すると
Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Linezolid belongs to Anti Bacterial; Ozanimod belongs to Central Nervous System.
なぜ起こるのか
Additive MAO inhibition and altered ozanimod metabolite exposure.
対処法
Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、LinezolidとOzanimodの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Linezolidのその他の相互作用
Ozanimodのその他の相互作用
よくある質問
Can I take Linezolid with Ozanimod?
MediHelp rates the interaction as contraindicated. Linezolid and Ozanimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod active metabolites are formed through MAO-B and may inhibit MAO, and linezolid is an MAO inhibitor. The combination may cause hypertensive crisis or serotonergic toxicity.
How serious is the interaction between Linezolid and Ozanimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose an alternative antibiotic. If unavoidable, monitor blood pressure and for serotonin toxicity.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
