相互作用
Magnesium gluconate + Misoprostol
重症度: 中等度
Magnesium gluconate and Misoprostol: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral magnesium salts have laxative properties and can worsen misoprostol-related diarrhea. Excess diarrhea may cause dehydration and poor tolerance of misoprostol.
この相互作用をわかりやすく説明すると
Magnesium gluconate and Misoprostol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive osmotic laxative effect of magnesium with misoprostol-induced intestinal secretion and motility.
対処法
Separate dosing is unlikely to remove the effect; consider whether the magnesium supplement is essential or reduce its dose. Monitor stool frequency and hydration.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Magnesium gluconateとMisoprostolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Misoprostolのその他の相互作用
よくある質問
Can I take Magnesium gluconate with Misoprostol?
MediHelp rates the interaction as moderate. Magnesium gluconate and Misoprostol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium salts have laxative properties and can worsen misoprostol-related diarrhea. Excess diarrhea may cause dehydration and poor tolerance of misoprostol.
How serious is the interaction between Magnesium gluconate and Misoprostol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate dosing is unlikely to remove the effect; consider whether the magnesium supplement is essential or reduce its dose. Monitor stool frequency and hydration.
What other medicines interact with Misoprostol?
MediHelp also lists interactions of Misoprostol with, for example, Oxytocin, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Misoprostol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。