相互作用
Methimazole + Potassium iodide
重症度: 中等度
Methimazole and Potassium iodide: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Both agents reduce thyroid hormone output, and iodide also inhibits hormone release. Together they can produce additive suppression, with a risk of hypothyroidism and goiter if used over a prolonged period. The combination is used deliberately for short periods, for example before thyroid surgery or in thyroid storm.
この相互作用をわかりやすく説明すると
Methimazole and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Methimazole belongs to Endocrine; Potassium iodide belongs to Endocrine.
なぜ起こるのか
Additive pharmacodynamic suppression of thyroid hormone synthesis and release.
対処法
Limit the combination to short, defined courses. Monitor thyroid function and watch for signs of hypothyroidism or goiter if therapy is prolonged.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MethimazoleとPotassium iodideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Methimazoleのその他の相互作用
Potassium iodideのその他の相互作用
よくある質問
Can I take Methimazole with Potassium iodide?
MediHelp rates the interaction as moderate. Methimazole and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents reduce thyroid hormone output, and iodide also inhibits hormone release. Together they can produce additive suppression, with a risk of hypothyroidism and goiter if used over a prolonged period. The combination is used deliberately for short periods, for example before thyroid surgery or in thyroid storm.
How serious is the interaction between Methimazole and Potassium iodide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit the combination to short, defined courses. Monitor thyroid function and watch for signs of hypothyroidism or goiter if therapy is prolonged.
What other medicines interact with Methimazole?
MediHelp also lists interactions of Methimazole with, for example, Carbamazepine, Clozapine, Propylthiouracil. The full list is on the Methimazole page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
