相互作用
Mycophenolic acid + Valganciclovir
重症度: 重大
Mycophenolic acid and Valganciclovir: major interaction.
最終更新日
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概要
Valganciclovir is converted to ganciclovir, and both drugs are myelosuppressive. Renal competition may also increase exposure to each, raising the risk of severe cytopenias.
この相互作用をわかりやすく説明すると
Mycophenolic acid and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Mycophenolic acid belongs to Miscellaneous; Valganciclovir belongs to Anti Virals.
なぜ起こるのか
Additive myelosuppression and competition for renal tubular secretion.
対処法
Monitor complete blood counts frequently, especially early in therapy, and adjust doses to renal function. Reduce or hold a drug if neutropenia or other cytopenias occur.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Mycophenolic acidとValganciclovirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Mycophenolic acidのその他の相互作用
Valganciclovirのその他の相互作用
よくある質問
Can I take Mycophenolic acid with Valganciclovir?
MediHelp rates the interaction as major. Mycophenolic acid and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valganciclovir is converted to ganciclovir, and both drugs are myelosuppressive. Renal competition may also increase exposure to each, raising the risk of severe cytopenias.
How serious is the interaction between Mycophenolic acid and Valganciclovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently, especially early in therapy, and adjust doses to renal function. Reduce or hold a drug if neutropenia or other cytopenias occur.
What other medicines interact with Mycophenolic acid?
MediHelp also lists interactions of Mycophenolic acid with, for example, Activated charcoal, Azathioprine, Cholestyramine. The full list is on the Mycophenolic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
