相互作用
Neomycin po + Vitamin B12
重症度: 中等度
Neomycin po and Vitamin B12: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral neomycin can reduce absorption of oral vitamin B12, and prolonged use may contribute to B12 deficiency. The effect is more relevant with extended courses.
この相互作用をわかりやすく説明すると
Neomycin po and Vitamin B12 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Neomycin causes mucosal injury and binds bile acids, impairing intestinal B12 uptake.
対処法
Monitor B12 status with prolonged neomycin therapy. Use parenteral B12 if deficiency develops.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Neomycin poとVitamin B12の臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Vitamin B12のその他の相互作用
よくある質問
Can I take Neomycin po with Vitamin B12?
MediHelp rates the interaction as moderate. Neomycin po and Vitamin B12 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral neomycin can reduce absorption of oral vitamin B12, and prolonged use may contribute to B12 deficiency. The effect is more relevant with extended courses.
How serious is the interaction between Neomycin po and Vitamin B12?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor B12 status with prolonged neomycin therapy. Use parenteral B12 if deficiency develops.
What other medicines interact with Vitamin B12?
MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Metformin. The full list is on the Vitamin B12 page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
