相互作用
Nevirapine + Ranolazine
重症度: 併用禁忌
Nevirapine and Ranolazine: contraindicated interaction.
最終更新日
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概要
Nevirapine may reduce ranolazine concentrations, risking loss of antianginal effect. Labeling contraindicates ranolazine with CYP3A inducers.
この相互作用をわかりやすく説明すると
Nevirapine and Ranolazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Nevirapine belongs to Anti Virals; Ranolazine belongs to Cardiovascular.
なぜ起こるのか
Nevirapine induces CYP3A4, increasing ranolazine clearance.
対処法
Avoid the combination. Use an alternative antianginal agent or a non-inducing antiretroviral.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、NevirapineとRanolazineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Nevirapineのその他の相互作用
Ranolazineのその他の相互作用
よくある質問
Can I take Nevirapine with Ranolazine?
MediHelp rates the interaction as contraindicated. Nevirapine and Ranolazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Nevirapine may reduce ranolazine concentrations, risking loss of antianginal effect. Labeling contraindicates ranolazine with CYP3A inducers.
How serious is the interaction between Nevirapine and Ranolazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Use an alternative antianginal agent or a non-inducing antiretroviral.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, St john's wort, Abemaciclib. The full list is on the Nevirapine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
