相互作用
Olsalazine + Warfarin
重症度: 軽度
Olsalazine and Warfarin: minor interaction.
最終更新日
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概要
Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.
この相互作用をわかりやすく説明すると
Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Olsalazine belongs to Gastrointestinal Tract; Warfarin belongs to Cardiovascular.
なぜ起こるのか
Possible small additive effect of salicylate on coagulation; mechanism not firmly established.
対処法
Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OlsalazineとWarfarinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Warfarinのその他の相互作用
よくある質問
Can I take Olsalazine with Warfarin?
MediHelp rates the interaction as minor. Olsalazine and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olsalazine is a salicylate-derived aminosalicylate, and salicylates have been reported to potentiate warfarin in isolated cases. Systemic exposure to the active mesalamine is low, so the effect is likely modest.
How serious is the interaction between Olsalazine and Warfarin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR after starting or stopping olsalazine and adjust warfarin if the INR changes.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
