相互作用
Oritavancin + Sirolimus
重症度: 軽度
Oritavancin and Sirolimus: minor interaction.
最終更新日
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概要
Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.
この相互作用をわかりやすく説明すると
Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oritavancin belongs to Anti Bacterial; Sirolimus belongs to Miscellaneous.
なぜ起こるのか
Weak CYP3A4 induction by oritavancin may modestly increase sirolimus clearance.
対処法
No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OritavancinとSirolimusの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Sirolimusのその他の相互作用
Oritavancinのその他の相互作用
よくある質問
Can I take Oritavancin with Sirolimus?
MediHelp rates the interaction as minor. Oritavancin and Sirolimus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer in vitro and could marginally lower sirolimus concentrations. Since oritavancin is given as a single dose, any effect is likely small and short-lived.
How serious is the interaction between Oritavancin and Sirolimus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is required. Check a sirolimus trough level if there is concern about reduced exposure.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Sirolimus page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
